Neubrandenburg (lit. New Brandenburg) is a city in the southeast of Mecklenburg-Vorpommern, Germany. It is located on the shore of a lake called Tollensesee and forms the urban centre of the Mecklenburg Lakeland.

The city is famous for its rich medieval heritage of Brick Gothic architecture, including the world's best preserved defensive wall of this style as well as a Concert Church (Saint Mary), the home venue of the Neubrandenburg Philharmonic. It is part of the European Route of Brick Gothic, a route which leads through seven countries along the Baltic Sea coast. Neubrandenburg is nicknamed for its four medieval city gates - "Stadt der Vier Tore" ("City of Four Gates").

Since 2011, Neubrandenburg has been the capital of the Mecklenburgische Seenplatte district. It is the third-largest city and one of the main urban centres of Mecklenburg-Vorpommern. The city is an economical node of northeastern Germany, featuring one of the highest national ranks in employment density and GDP per capita. The closest greater urban areas are the regiopolis of Rostock and the metropolises of Szczecin, Berlin and Hamburg. Since 1991, Neubrandenburg has hosted a University of Applied Sciences that offers international exchanges, guest programs and study programs.

Neubrandenburg has preserved its medieval city wall in its entirety. The wall, 7 m high with a perimeter of 2.3 km, has four Brick Gothic city gates, dating back to the 14th and 15th centuries. Of these, one of the most impressive is the Stargarder Tor, with its characteristic gable-like shape and the filigree tracery and rosettes on the outer defence side.

Another place of interest is the Brick Gothic Marienkirche (Church of the Virgin Mary or St. Mary's Church, Konzertkirche), completed 1298. The church was nearly destroyed in 1945, but it was restored in 1975 and now houses a concert hall (opened 2001).

The tallest highrise in the city is the 56m Haus der Kultur und Bildung (HKB, House of Culture & Education), opened in 1965. Its slender appearance has earned it the nickname Kulturfinger ("culture finger").

Other attractions include Neubrandenburg Regional Museum.