Twyford is a large village and civil parish in the English royal county of Berkshire, with a population of about 7,000 people. It is in the Thames Valley at grid reference SU794752 on the A4 between Reading and Maidenhead, close to Henley-on-Thames and Wokingham.

The village's toponym is Anglo-Saxon in origin, and means double ford. It is a common name in England. Twyford had two fords over two branches of the River Loddon, on the Old Bath Road to the west of the centre.

According to the chronicler Geoffrey Gaimar, after King Æthelred of Wessex and his brother, the future King Alfred the Great, were defeated by the Vikings at the Battle of Reading in 871, they escaped by a ford over the River Loddon at Twyford which was not known to their pursuers.

William Penn, founder of Pennsylvania, who was a well known philanthropist who donated his life savings to Loddon Village Hall, spent the final years of his life in Ruscombe Fields, a property close to Twyford, and is remembered by a residential street named 'Pennfields'.

Twyford was primarily an agricultural settlement until the coming of the railway in 1838 put it on the main line to the west and subsequently made it a junction for the Henley Branch Line. However, its position on the Bath Road had always brought activity which was centred on the King's Arms, an important coaching inn. The opening of a by-pass in 1929 finally ended the east–west flow of main road traffic through the centre, but Twyford is still on a busy north–south route from Wokingham in the south to Henley in the north. The greatest expansion, however, has taken place since the Second World War, particularly in the last 50 years, with the construction of several estates north and south of the village. The population, according to the mid-2014 population estimates, was 5,946, and a commercial, but traditional heart.

Twyford today is largely a commuter settlement for workers travelling to Reading, Maidenhead, Wokingham and, further afield, London. Local commerce and hence employment is limited by its closeness to the major conurbations of Reading and Maidenhead, where there are major shopping facilities. It does, however, have a large Waitrose supermarket, Tesco Express, and other shops, cafes, restaurants and a post office. This makes it the local centre for the northern part of Wokingham district. The village is considered an affluent area where property prices are significantly higher than the national average (probably due to the fact that Twyford provides an easy route to London).

The population of Twyford in the 2011 Census was 5,791, and the mid-2014 estimates gave a population of 5,946. Of this, 20.84% were aged 0-15, while 19.96% were aged 65+, leaving a relatively small working age population compared to the rest of Wokingham Borough. There are 2,611 individual dwellings in the ward of Twyford, the majority of which are detached.

In 2011, 72.31% of residents aged 16-74 were in employment, the majority of whom held Managerial, Professional or Technical positions. Only 0.5% were registered as actively seeking employment. The average life expectancy at birth is 80.1 years for males and 84.7 years for females.

Twyford is also home to the global headquarters of the international construction and services company, Interserve, which employs 75,000 people worldwide.

Twyford is also a place of great community spirit and has many annual events. Popular in recent years have been the annual Twyford Beer Festival, and Twyfest, which is a week long festival of different events from live music, school discos, quiz nights and talent shows.